“Whatever he did to her, it busted her up to the core,” says the Full House star.

October 21, 2025: John Stamos, famously known as “Uncle Jesse” from Full House, has spoken out about Lori Loughlin’s estranged husband Mossimo Giannulli, calling him a “terrible narcissist” and expressing concern over the emotional toll on the actress. Stamos described Loughlin as “a saint” and said the separation and past events have had a profound impact on her.

Stamos Breaks His Silence

During a recent episode of the Good Guys podcast, Stamos shared his longtime admiration and loyalty to Loughlin, highlighting:

He’s known Lori Loughlin for around 40 years and regards her as a “good person, a good mother, a good wife.”

“I’m just heartbroken for her right now,” he said, referencing the fallout from her marriage and past controversies.

He added, “Whatever he did to her, it busted her up to the core. She put up with a lot over the years of this guy.”

Regarding Giannulli, Stamos stated firmly: “I will never talk to him again.”

The Context: Marriage, Scandal, and Separation

Loughlin and Giannulli were married for nearly 28 years and share two daughters. Their marriage became highly publicized due to the 2019 “Operation Varsity Blues” college admissions scandal:

The couple pleaded guilty to mail and wire fraud, paying nearly $500,000 to secure their daughters’ admission to USC under false pretenses.

Loughlin served two months in prison, while Giannulli served five months.

Stamos’ comments suggest he believes Giannulli was the driving force behind the scandal and that Loughlin endured disproportionate blame and scrutiny.

Why This Matters

Celebrity support: Stamos’ open condemnation of Giannulli is significant, showing loyalty and shifting public perception toward Loughlin.

Humanizing the scandal: The focus moves from legal consequences to the emotional and personal toll on those involved.

Public vs. private life: The situation underscores how fame, scandal, and personal relationships intertwine, often leaving long-lasting emotional impacts.

What’s Next?

Loughlin continues to rebuild her personal life and career with support from friends and colleagues.

Giannulli faces ongoing public criticism, particularly from Loughlin’s allies and longtime friends.

Media coverage may increasingly focus on the human story behind the headlines, beyond the college admissions scandal.