Ryan Reynolds leads a star-studded cast as Deadpool 3 officially brings the Merc with a Mouth into the Marvel Cinematic Universe.

Deadpool 3 Cast

December 6, 2025: Deadpool 3 is one of the most highly anticipated Marvel films to date, marking the official MCU debut of the R-rated franchise while reuniting fan-favorite characters and introducing major new faces. With a mix of returning stars, shocking cameos, and Marvel legends crossing universes, the cast lineup has become a trending topic across entertainment headlines.

Ryan Reynolds Returns as Deadpool

Ryan Reynolds reprises his iconic role as Wade Wilson / Deadpool, once again serving as the heart and chaos of the franchise. Known for breaking the fourth wall and skewering superhero tropes, Reynolds remains central to the film’s tone — even as Deadpool 3 expands into multiverse territory.

Hugh Jackman Joins as Wolverine

In one of the most surprising announcements in recent Marvel history, Hugh Jackman returns as Logan / Wolverine. Despite previously retiring the character after Logan, Jackman’s involvement has electrified fans, signaling a major multiverse twist and redefining Wolverine’s place within the MCU.

Familiar Faces From the Deadpool Universe

Several beloved characters are confirmed or widely reported to return:

Morena Baccarin as Vanessa Carlysle, Wade’s longtime love

Stefan Kapičić as Colossus, the X-Men powerhouse

Brianna Hildebrand as Negasonic Teenage Warhead

Shioli Kutsuna as Yukio

Leslie Uggams as Blind Al

Karan Soni as Dopinder, the fan-favorite cab driver

These returns ensure the film retains the humor, relationships, and emotional beats that defined the earlier entries.

Emma Corrin Steps In as the Villain

Emma Corrin joins the franchise in a major villain role, widely believed to be Cassandra Nova, a powerful and deeply unsettling foe with ties to X-Men lore. Corrin’s casting has drawn strong buzz, with many expecting a chilling and complex antagonist performance.

Matthew Macfadyen’s Mystery MCU Role

Matthew Macfadyen has been cast in an undisclosed role believed to be linked to the Time Variance Authority. His presence strengthens connections to the wider MCU and suggests deeper exploration of multiverse consequences.

Cameos and Surprise Appearances

As with any multiverse-driven Marvel project, Deadpool 3 is surrounded by cameo speculation. While Marvel has not confirmed details, fans continue to theorize about appearances from MCU characters, legacy X-Men faces, and unexpected crossover moments.

Marvel Studios has remained tight-lipped, fueling anticipation for surprise reveals.

A Cast Bridging Marvel Eras

What sets Deadpool 3 apart is how its cast bridges multiple superhero eras — Fox’s X-Men universe, Deadpool’s standalone franchise, and the current MCU. This bold combination signals not just a sequel, but a major turning point for Marvel storytelling.

With Ryan Reynolds’ irreverent humor, Hugh Jackman’s legendary return, and a strong ensemble backing them, Deadpool 3 is shaping up to be one of Marvel’s biggest and most talked-about releases.