Previcox is a commonly prescribed medication for dogs suffering from pain and inflammation caused by conditions such as osteoarthritis, post-operative pain, and other musculoskeletal disorders. It includes firocoxib and is a member of the non-steroidal anti-inflammatory medicine (NSAID) class of medications.

As dogs age, they become more prone to developing degenerative joint diseases that cause inflammation and pain. Such diseases can make it difficult for dogs to move around and perform daily activities, significantly impacting their quality of life. Fortunately, Previcox can be a useful tool in managing these chronic conditions, providing effective pain relief and improving mobility.

In this article, we will discuss the benefits of using Previcox in dogs, how it works, precautions and potential side effects, as well as the proper use and dosage of the medication.

How Does Previcox Work?

Previcox is an anti-inflammatory medication (NSAID) that includes the active component firocoxib. It is commonly used in veterinary medicine for pain management in dogs with osteoarthritis or other conditions that cause pain and inflammation.

The active ingredient in Previcox, firocoxib, selectively inhibits the COX-2 enzyme, which is responsible for producing prostaglandins that cause pain and inflammation. COX-2 enzymes are found primarily in areas of inflammation and injury, making them a target for pain management.

By selectively inhibiting the COX-2 enzyme, Previcox reduces pain and inflammation in affected tissues without significantly affecting the COX-1 enzyme, which is responsible for maintaining healthy gastrointestinal function. 

Previcox can take several days to reach its full effectiveness and should not be used in combination with other NSAIDs or corticosteroids without the guidance of a veterinarian. 

Benefits of Previcox in Dogs

Previcox can be used to manage pain and inflammation associated with various conditions, including osteoarthritis, post-operative pain, and other musculoskeletal disorders. As compared to other NSAIDs, it has been demonstrated to give excellent pain relief with fewer gastrointestinal side effects.

In March 2022, Previcox was approved by the U.S. Food and Drug Administration (FDA) as an easy-to-administer chewable tablet, providing a more convenient way for pet owners to give their dogs the medication. The new chewable tablet form of Previcox also ensures that dogs receive the full dose of medication, as the tablet is easily broken down and absorbed in the stomach.

Previcox has been shown to be a promising option for managing chronic pain in dogs with osteoarthritis. In fact, a 2022 article on reported that many veterinarians frequently recommend Previcox to treat the symptoms of osteoarthritis in dogs.

Previcox has also been shown to be effective in managing pain and inflammation associated with other conditions, such as soft tissue injuries.

Precautions and Side Effects 

Previcox should only be used under the supervision of a veterinarian, as it can have potential side effects such as gastrointestinal upset, liver and kidney problems, and changes in blood cell count. It is critical to carefully follow your veterinarian’s recommendations and report any bad reactions or abnormalities in your dog’s health while on Previcox.

In rare cases, Previcox can cause severe allergic reactions, including hives, facial swelling, and difficulty breathing. If your dog experiences any of these symptoms, seek veterinary care immediately.

It is also important to note that according to a report on, using Previcox at doses above the recommended 2.27 mg/lb (5.0 mg/kg) in puppies that are seven months old or less, has been linked to serious adverse reactions, including death. 

Additionally, Previcox should not be used in dogs with a known hypersensitivity to firocoxib or any other NSAIDs. It should also be avoided in dogs with pre-existing liver, kidney, or cardiovascular disease, as well as in pregnant or lactating dogs, unless specifically recommended by a veterinarian. 

It is important to disclose your dog’s medical history and any other medications they are taking to your veterinarian before starting treatment with Previcox to avoid potential interactions or complications. Previcox should only be used in accordance with the advice of a licensed veterinarian, as is the case with other medications. It is important to weigh any potential benefits against any potential risks.


Previcox can be a useful tool in managing pain and inflammation in dogs, but it is important to use it carefully and under the guidance of a veterinarian. Knowing how Previcox works and the potential negative effects can allow you to make more educated decisions regarding your dog’s health.

Always consult with your veterinarian before giving your dog any medication, including Previcox. Previcox can help your dog go from pain to gain and improve their overall quality of life with proper use.

Published by HOLR Magazine.